Adcirca

ADCIRCA (pronounced AD-SUR-KUH) is a prescription medicine called a phosphodiesterase 5 inhibitor (PDE-5i), used to treat pulmonary arterial hypertension (PAH) to improve exercise ability.
• ADCIRCA is the only PDE-5i for PAH taken once-daily
• ADCIRCA may improve exercise ability

After 16 weeks of treatment, patients taking ADCIRCA increased their 6-minute walk distance (6MWD) by an average of 33 meters, or 108 feet
The most common side effects of ADCIRCA are headache, muscle pain, getting red or hot in the face (flushing), nausea, pain in the arms, legs or back, upset stomach, stuffy or congested nose

The maximum co-pay for ADCIRCA is $20 for eligible patients on commercial/private insurance plans*
* This program is not valid for prescriptions reimbursed under Medicare, Medicaid, VA, DoD (TRICARE), Indian Health Services, or similar federal or state programs, or for patients in the state of Massachusetts. This program pays the difference of any co-pays above $20, up to $800 monthly, directly to the pharmacy.

Important Safety Considerations for ADCIRCA® (tadalafil) tablets
• You should discuss all of your medical conditions and all medications with your healthcare provider before starting ADCIRCA
• Do not take ADCIRCA if you take any medications that contain nitrates (often used for chest pain), as the combination could cause a sudden, unsafe drop in blood pressure
• Do not take ADCIRCA if you are allergic to tadalafil or any other ingredient in ADCIRCA
• If you experience chest pain after taking ADCIRCA, contact your healthcare provider
• ADCIRCA is a type of medication called a phosphodiesterase 5 inhibitor (PDE-5i). PDE-5is can cause blood vessels to widen, which may result in a decrease in blood pressure. If you have heart-disease or any problems with low blood pressure, tell your healthcare provider before taking ADCIRCA, as these conditions may be affected by the action of ADCIRCA
• If you have ever had blockage in the veins of your lungs, known as pulmonary veno-occlusive disease (PVOD), ADCIRCA is not recommended for you
• Taking ADCIRCA with alcohol, or blood pressure medications, such as alpha-blockers, may lower blood pressure and cause hypotension (light-headedness or fainting)
• Do not take ADCIRCA if you are taking rifampin (an antibiotic for certain bacterial infections), or antifungal medications, such as ketoconazole and itraconazole. If you require treatment with both ADCIRCA and ritonavir (Norvir®) at the same time, your dose of ADCIRCA will need to be adjusted. Inform your healthcare provider if you have kidney or liver problems before taking ADCIRCA
• ADCIRCA contains the same ingredient (tadalafil) as Cialis®, which is used to treat erectile dysfunction (impotence). If you are taking ADCIRCA, do not take Cialis or other PDE-5is
• In rare cases, men taking PDE-5is (including tadalafil) for erectile dysfunction reported side effects such as a sudden decrease or loss of vision or hearing, or an erection lasting more than four hours. If you experience any of these side effects, seek medical attention right away
• The most common side effects of ADCIRCA are headache, muscle pain, getting red or hot in the face (flushing), nausea, pain in the arms, legs or back, upset stomach, stuffy or congested nose